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: Cysteine Sulfenylation of Protein Disulfide Isomerase Links Oxidative Stress to Thrombosis

Researchers

Presenter

  • Moua Yang

Principal Investigators

  • James Flaumenhaft

  • Christina Scartelli

  • Sachin Patel

  • Kate S Carroll

  • Brian C Smith

  • Nicola Pozzi

  • Robert Flaumenhaft

Medical Centers

  • Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI

  • Department of Chemistry, University of Florida Scripps Biomedical Research, Jupiter, FL

  • Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center and Harvard Medical School, Newton, MA

  • Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University, Saint Louis, MO

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Pulmonary/Respiratory Diseases

  • Cardiovascular (CVS)

  • Blood/haematological Diseases

Disease

  • Dyslipidemia

  • Venous thrombosis

Biomarkers

  • Nucleoside diphosphate kinase A

  • Immunoglobulin G

Drug/Treatment

  • Hydrogen peroxide

  • releasate

  • Cysteine Hydrochloride

  • Evithrom

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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