// App-Quantinova.ai

: Anti-CD70 Monoclonal Antibodies Show Efficacy in Preclinical Models for Chronic Lymphoblastic Leukemia

Researchers

Presenter

  • Shih-Shih Chen

Principal Investigators

  • Xiao-Jie Yan

  • Luc Van Rompaey

  • Piotr Zabrocki

  • Nicholas Chiorazzi

Medical Centers

  • Karches Center for Oncology Research, The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY

Locations

  • Belgium

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Chronic Lymphocytic Leukemia

Biomarkers

  • Bruton tyrosine kinase

  • Breakpoint Cluster Region

  • C-C Motif Chemokine Receptor 7

  • Cluster of Differentiation 5

  • Cytotoxic T-lymphocyte-associated protein 4

  • Cluster of differentiation 69

  • Programmed death-ligand 1

  • Interleukin 10

  • Interleukin 4

  • Tumor necrosis factor

  • T helper 2

  • Type 1 T helper

Drug/Treatment

  • Interferon Gamma

  • Ibrutinib

  • Allopurinol

  • Interleukin-10

Outcome

  • N/A


Study Design

  • Efficacy

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A