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: Lenalidomide-Rituximab or Lenalidomide-Rituximab-Bendamustine in Patients with Relapsed/Refractory Follicular Lymphoma: Priimary Analysis of the Randomized Phase II HOVON110/Rebel Trial

Researchers

Presenter

  • Marie Jose Kersten

Principal Investigators

  • Kim M. Linton

  • Dana Chitu

  • Sanne Tonino

  • Marcel Kap

  • Roberto D Liu

  • Martine E.D. Chamuleau

  • Hein P.J. Visser

  • Eva de Jongh

  • Erik WAF Marijt

  • Maria B.L. Leijs

  • Yavuz M. Bilgin

  • Jan Durig

  • Pamela McKay

  • Tjeerd J.F. Snijders

  • Andrew Pettitt

  • Monique C. Minnema

  • Gabriele Prange-Krex

  • Maria Cuijpers

  • Lara H. Böhmer

  • Lidwine W. Tick

  • Axel Florschutz

  • Matthijs Silbermann

  • Rob Fijnheer

  • Aart Beeker

  • Nelleke Tolboom

  • Cristina Mitea

  • Anne IJ Arens

  • Gerben JC Zwezerijnen

  • Wolfram Klapper

  • Sarah E. Coupland

  • Daphne de Jong

  • Jeanette K. Doorduijn

  • Josée M. Zijlstra

Medical Centers

  • Dept of Hematology, Lymmcare, Cancer Center Amsterdam, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, Netherlands

  • Hematology, Leiden University Hospital, Leiden, Netherlands

  • Maasstad Ziekenhuiis, Rotterdam, Netherlands

  • HOVON Data Center, Erasmus MC Cancer Institute, Department of Hematology, Rotterdam, Netherlands

  • Department of Hematology, Albert Schweitzer Hospital, Dordrecht, Netherlands

  • Amsterdam UMC, University of Amsterdam, Amsterdam, NLD

  • Pathology, University of Liverpool, Liverpool, GBR

  • Medisch Spectrum Twente, Enschede, Netherlands

  • Ter Gooi Hospital, HILVERSUM, NLD

  • Gemeinschaftspraxis Mohm/Prange-Krex, Dresden, Germany

  • Beatson West of Scotland Cancer Centre, Glasgow, United Kingdom

  • Nuclear Medicine, Maastricht University Medical Center, Maastricht, Netherlands

  • The Clatterbridge Cancer Centre NHS Foundation Trust, Liverpool, United Kingdom

  • University of Liverpool, Liverpool, United Kingdom

  • Hematology, Medisch Centrum Alkmaar, Alkmaar, NLD

  • Department of Medicine III, Klinikum Der Universitaet Muenchen-Campus Grosshadern, Munich, Germany

  • Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, Netherlands

  • Department of Hematology, University Medical Center, Utrecht, Netherlands, Utrecht, Netherlands

  • Nuclear Medicine, University Medical Center Utrecht, Utrecht, Netherlands

  • Hematology, Klinikum Dessau, Dessau, Germany

  • Department of Hematology, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam, the Netherlands, Amsterdam, Netherlands

  • Department of Internal Medicine, Admiraal de Ruijter Hospital, Goes, Netherlands

  • Spaarne Ziekenhuis, Hoofddorp, Netherlands

  • Amsterdam University Medical Centers, Location University of Amsterdam; Cancer Center Amsterdam, Amsterdam, Netherlands

  • Department of Hematology, Essen University Hospital, Essen, Germany

  • Amsterdam UMC, Vrije Universiteit Amsterdam, department of Pathology, Cancer Center Amsterdam, Amsterdam, Netherlands

  • Division of Cancer Sciences, University of Manchester and the Christie Hospital, Manchester, United Kingdom

  • Viecuri Medical Centre, Venlo, NLD

  • Department of Hematology, Haga Teaching Hospital, The Hague, Netherlands

  • Maxima Medical Center, Veldhoven, NLD

  • University Hospital Schleswig-Holstein, Campus Kiel, Kiel, DEU

  • Meander Medical Center, Department of Internal Medicine, Amersfoort, Netherlands

  • HOVON Data center, Dept. of Hematology, ErasmusMC Cancer Institute, Rotterdam, Netherlands

  • Department of Radiology and Nuclear Medicine, Amsterdam UMC, Location VUmc, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam, Netherlands

  • Radboud University Medical Center, Nijmegen, NLD

Locations

  • Netherlands

  • Germany

  • United Kingdom

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Pulmonary/Respiratory Diseases

  • Cardiovascular (CVS)

  • Oncology (ONC)

  • Blood/haematological Diseases

Disease

  • Follicular lymphoma

  • Thrombocytopenia

  • Neutropenia

  • Venous thrombosis

  • Lymphomas

Biomarkers

  • Granulocyte colony-stimulating factor

Drug/Treatment

  • Trimethoprim and sulfamethoxazole

  • Bendamustine

  • Zelitrex

  • Lenalidomide

  • Rituximab

  • Filgrastim

Outcome

  • N/A

Study Design

  • Randomized

  • Efficacy

  • Double Blind/Blinded

  • Non-Comparative

  • Multicenteric

  • Prospective

Phase

  • II

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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