// App-Quantinova.ai

: PAX5 Epigenetically Orchestrates CD58 Transcription and Modulates Blinatumomab Response in Acute Lymphoblastic Leukemia

Researchers

Presenter

  • Yizhen Li

Principal Investigators

  • Takaya Moriyama

  • Satoshi Yoshimura

  • Xuijie Zhao

  • Zhenhua Li

  • Xu Yang

  • Jacob A Steele

  • Shondra Miller

  • Elisabeth Paietta

  • Marina Konopleva

  • JiYang Yu

  • Hiroto Inaba

  • Raul C Ribeiro

  • Ching-Hon Pui

  • Jun J. Yang

Medical Centers

  • Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Bartlett, TN

  • Cancer Center, Montefiore Medical Center, Bronx, NY

  • Department of Leukemia, The University of Texas M.D. Anderson Cancer Center, Houston, TX

  • Center for Advanced Genome Engineering, St Jude Children's Research Hospital, Memphis, TN

  • Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • B-cell acute lymphoblastic leukemia

Biomarkers

  • Cluster of Differentiation 2AP

Drug/Treatment

  • Blinatumomab

Outcome

  • N/A

Study Design

  • Adaptive

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

Copyright © 2026. QuantiNova All rights reserved