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: Homoharringtonine Synergizes Strongly with Venetoclax Against the Early T-Cell Progenitor Acute Lymphoblastic Leukemia：from Bench to Bed

Researchers

Presenter

  • Shanshan Suo

Principal Investigators

  • Jiejing Qian

  • Dandan Zhao

  • Wenjuan Yu

  • YinJun Lou

  • Honghu Zhu

  • Hongyan Tong

  • Min Yang

  • Xin Huang

  • Shuqi Zhao

  • Junjing Qiao

  • Chen Liang

  • Fenglin Li

  • Huafeng Wang

  • Yi Zhang

  • Le Xuan Truong Nguyen

  • Dinh Hoa Hoang

  • Fang Chen

  • Jie Sun

  • Ivan Rodriguez

  • Lucy Ghoda

  • Ling Li

  • Bin Zhang

  • Guido Marcucci

  • Jie Jin

Medical Centers

  • Department of Hematological Malignancies Translational Science, Gehr Family Center for Leukemia Research, Hematology Malignancies and Stem Cell Transplantation Institute, Beckman Research Institute, City of Hope, Duarte, CA

  • Department of Hematology, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China

Locations

  • United States

  • China

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Endocrine/metabolic Diseases (ME)

Disease

  • Acute lymphoblastic leukemia

  • Tumor lysis syndrome

  • T-cell acute lymphoblastic leukemia

Biomarkers

  • B-cell lymphoma 2

  • Myeloid Cell Leukemia 1

  • Granulocyte colony-stimulating factor

Drug/Treatment

  • Omacetaxine mepesuccinate

  • Cytarabine liposomal

  • Venetoclax

  • Filgrastim

Outcome

  • N/A

Study Design

  • Multicenteric

  • Cohort

Phase

  • I

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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