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: Native Stem Cell Transcriptional Circuits in Normal and Malignant Early-Stage T Cells

Researchers

Presenter

  • Mark Y Chiang

Principal Investigators

  • Qing Wang

  • Carea Mullin

  • Elizabeth Choe

  • Nicole Dean

  • Fatema Akter

  • Siyi Chen

  • Ashley Melnick

  • Anna McCarter

  • Rohan Kodgule

  • Raghu Vannam

  • Christopher J. Ott

  • Russell J.H. Ryan

Medical Centers

  • Biostatistics Department, University of Michigan, Ann Arbor

  • Cellular and Molecular Biology Graduate Program, University of Michigan, Ann Arbor

  • MGH Cancer Center, Charlestown, MA

  • Massachussets General Hospital, Cambridge

  • Department of Pathology, University of Michigan Medical School, Ann Arbor, MI

  • Hematology-Oncology, University of Michigan, Ann Arbor, MI

  • University of Michigan, Ann Arbor

  • Stanford University, Palo Alto

  • Department of Internal Medicine, University of Michigan, Ann Arbor

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Solid malignancies

  • T-cell acute lymphoblastic leukemia

Biomarkers

  • Neurogenic locus notch homolog protein 1

  • MYCN proto-oncogene, bHLH transcription factor

  • B-cell lymphoma 2

  • MYB proto-oncogene, transcription factor

  • cMYC

Drug/Treatment

  • Venetoclax

  • Anascorp Centruroides scorpion

  • folitixorin calcium

Outcome

  • N/A


Study Design

  • N/A

Phase

  • I

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A