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: High-Dose Methotrexate Is Not Associated with Reduction in CNS Relapse in Patients with Aggressive B-Cell Lymphoma: An International Retrospective Study of 2300 High-Risk Patients

Researchers

Presenter

  • Katharine Louise Lewis

Principal Investigators

  • Diego Villa

  • Sabela Bobillo

  • Karin Ekstroem Smedby

  • Kerry J. Savage

  • Toby A. Eyre

  • Kate Cwynarski

  • Paris L Caporn

  • Joan Van Zyl

  • Magdalena Klanova

  • Marek Trneny

  • Robert Puckrin

  • Douglas A. Stewart

  • Mark J Bishton

  • Christopher P. Fox

  • Aung M Tun

  • Gita Thanarajasingam

  • Faouzi Djebbari

  • Erel Joffe

  • Sandra Eloranta

  • Sara Harrysson

  • Laurie H. Sehn

  • Seth M Maliske

  • Kittika Poonsombudlert

  • Xiao Guo

  • Greg Hapgood

  • Kate Manos

  • Eliza Hawkes

  • Jahanzaib Khwaja

  • Adrian Minson

  • Michael Dickinson

  • Andreas Kiesbye Øvlisen

  • Gareth P Gregory

  • Michael Gilbertson

  • Isaac T Streit

  • Hamish W Scott

  • Matthew Ku

  • Sanjay de Mel

  • kar ying Yong

  • Liu Xin

  • Mridula Mokoonlall

  • Dipti Talaulikar

  • Nicholas L McVilly

  • Anna Johnston

  • Matthew J Brunner

  • Priyanka A Pophali

  • Matthew J. Maurer

  • Tarec Christoffer El-Galaly

  • Chan Yoon Cheah

Medical Centers

  • First Dept. of Medicine- Hematology, Charles University General Hospital and First Faculty of Medicine, Praha , Czech Republic

  • National University Health System, Kent Ridge, Singapore

  • Department of Oncology, University of Calgary, Tom Baker Cancer Centre, Calgary, Canada

  • Department of Haematology-Oncology, National University Cancer Institute, Singapore, Singapore, Singapore

  • BC Cancer Centre for Lymphoid Cancer and The University of British Columbia, Vancouver, Canada

  • Department of Haematology, Sir Charles Gairdner Hospital, West Leederville, Australia

  • Department of Haematology, Monash Health, Melbourne, Australia

  • Linear Clinical Research, Perth, Australia

  • Department of Haematology, Royal Hobart Hospital, Hobart, Australia

  • Department of Clinical Haematology, Austin Health, Heidelberg, Australia

  • Holden Comprehensive Cancer Center, University of Iowa Hospital and Clinics, Iowa city, IA

  • Division of Hematology, Department of Medicine, University of Wisconsin- Carbone Cancer Center, Madison, WI

  • Tom Baker Cancer Centre, Calgary, Canada

  • Department of Haematology, The Canberra Hospital, Canberra, Australia

  • Carbone Cancer Center, Madison

  • Department of Medicine, Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY

  • Division of Hematology, University of Wisconsin, Madison, Madison, WI

  • Mayo Clinic, Division of Hematology, Rochester, MN, USA, Rochester, MN

  • Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom

  • Department of Medicine Solna, Division of clinical epidemiology, Karolinska Institutet, Stockholm, Sweden

  • Cancer and Haematology Centre, Oxford University Hospitals NHS Foundation Trust, Old Road, United Kingdom

  • Department of Clinical Haematology, Peter MacCallum Cancer Centre, Melbourne, Australia

  • Department of Oncology, University of Calgary, Calgary, Canada

  • Department of Haematology, University College London Hospitals NHS Foundation Trust, London, United Kingdom

  • Centre for Lymphoid Cancer, British Columbia Cancer Agency, Vancouver, Canada

  • Monash Haematology, Monash Health, Melbourne, Australia

  • University of Melbourne, Melbourne, Australia

  • Department of Haematology, St Vincent's Hospital and University of Melbourne, Melbourne, Australia

  • University of Western Australia, Perth, AUSTRALIA

  • First Deptartment of Internal Medicine - Hematology, General University Hospital and First Faculty of Medicine, Charles University, Prague, Czech Republic

  • Princess Alexandra Hospital, Brisbane, Australia

  • Department of Haematology, St Vincent's Hospital, Melbourne, Australia, Melbourne, Australia

  • Urologicka Klinika, Vseobecna Fakultni Nemocnice, Interni Klinika-Klinika Hematologie, Prague, Czech Republic

  • Department of Hematology, Clinical Cancer Research Center, Aalborg University Hospital, Aalborg, Denmark

  • Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom

  • Department of Haematology, University College London Hospital NHS Foundation Trust, London, United Kingdom

  • Royal Melbourne Hospital, Melbourne, Australia

  • st Internal Department - Department of Haematology, General University Hospital, Prague, Czech Republic

  • Mayo Clinic, Division of Clinical Trials and Biostatistics, Rochester, MN, USA, Rochester, MN

  • University of Tasmania, Hobart, Australia

  • Division of Hematology, Oncology, and Blood & Marrow Transplantation, University of Iowa Hospital and Clinics, Iowa City, IA

Locations

  • Czech Republic

  • Australia

  • Singapore

  • Canada

  • United Kingdom

  • United States

  • Denmark

  • Sweden

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Diffuse large B-cell lymphoma

Biomarkers

  • B-cell lymphoma 2

  • B-cell lymphoma 6

  • cMYC

Drug/Treatment

  • Methotrexate

Outcome

  • N/A

Study Design

  • Multinational

  • Multicenteric

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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