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: Synergistic Activity of BH3-Mimetics By Combined Targeting of Anti-Apoptotic Regulators in B-Cell Precursor ALL

Researchers

Presenter

  • Felix Seyfried

Principal Investigators

  • Felix Stirnweiß

  • Alexandra Niedermayer

  • Stefanie Enzenmuller

  • Rebecca Horl

  • Stefan Kohrer

  • Klaus-Michael Debatin

  • Luder Hinrich Meyer

Medical Centers

  • Department of Pediatric Hematology and Oncology, St. Anna Children's Hospital, Vienna, Austria

  • Department of Pediatrics and Adolescent Medicine, Ulm University Medical Center, Ulm, Germany

Locations

  • Austria

  • Germany

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • B cell lymphomas

Biomarkers

  • BCL2 like 11

  • BCL2 associated X, apoptosis regulator

Drug/Treatment

  • Venetoclax

Outcome

  • N/A


Study Design

  • Dose Response

  • Controlled

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A