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: Repurposing NAD Salvage Inhibitors for GCB Diffuse Large-B Cell Lymphoma

Researchers

Presenter

  • Claudio Scuoppo

Principal Investigators

  • Bowen Cai

  • Kenneth Ofori

  • Hanna Scholze

  • Katia Basso

  • Laura Pasqualucci

  • Riccardo Dalla-Favera

Medical Centers

  • Department of Microbiology & Immunology, Columbia University, New York, NY

  • Department of Pathology & Cell Biology, Columbia University, New York, NY

  • Institute for Cancer Genetics, Columbia University, New York, NY

  • Herbert Irving Comprehensive Cancer Center, Columbia University, New York, NY

  • Department of Genetics & Development, Columbia University, New York, NY

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • B-cell acute lymphoblastic leukemia

  • Diffuse large B-cell lymphoma

  • Acute lymphoblastic leukemia

  • Chronic Myelogenous Leukemia

  • B cell lymphomas

  • Lymphomas

Biomarkers

  • B-cell lymphoma 2

  • Enhancer of zeste homolog 2

  • Kynurenine

Drug/Treatment

  • Nicotinamide

  • dasatinib

  • FK866

  • EZH2

Outcome

  • N/A

Study Design

  • Safety

  • Dose Response

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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