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: The Deglycosylated Form of 1E12, a Monoclonal Anti-PF4 IgG, Strongly Inhibits Antibody-Triggered Cellular Activation in Vaccine-Induced Thrombotic Thrombocytopenia, and Is a Potential New Treatment for Vιττ

Researchers

Presenter

  • Caroline Vayne

Principal Investigators

  • Raghavendra Palankar

  • Sandra Billy

  • Stefan Handtke

  • Thomas Thiele

  • Claire Pouplard

  • Andreas Greinacher

  • Yves Gruel

  • Jerome Rollin

Medical Centers

  • University of Tours, Tours, France

  • Greifswald University Hospital, Greifswald, Germany

  • Institute for Immunology and Transfusion Medicine, University Medicine Greifswald, Greifswald, Germany

  • Department of Hematology-Hemostasis, University Hospital of Tours, Tours, France

Locations

  • France

  • Germany

Companies

  • N/A

Study Components

Therapeutic Area

  • Blood/haematological Diseases

  • Pulmonary/Respiratory Diseases

  • Cardiovascular (CVS)

Disease

  • Thrombocytopenia

  • Venous thrombosis

Biomarkers

  • Immunoglobulin G

  • Serotonin

Drug/Treatment

  • Heparin

  • IdeS

  • Ogen

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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