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DDRE-47 : ASSESSMENT OF BRAIN PENETRANCE, BIODISTRIBUTION, AND EFFICACY OF PLATINUM (IV)-CONJUGATED FLUORINATED MACROCYCLIC CELL-PENETRATING PEPTIDES IN A MURINE GLIOBLASTOMA MODEL

Researchers

Presenter

  • Jorge Jimenez Macias

Principal Investigators

  • Yen-Chun Lee

  • Tomer Finkelberg

  • Mykola Zdioruk

  • Gilles Berger

  • Michal Nowicki

  • Choi-Fong Cho

  • Bogdan Fedeles

  • Andrei Loas

  • Bradley Pentelute

  • Sean Lawler

Medical Centers

  • Microbiology, Bioorganic and Macromolecular Chemistry, Faculty of Pharmacy, Université Libre de Bruxelles, Brussels, Belgium

  • Harvey Cushing Neurooncology Laboratories, Neurosurgery Department, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA

  • Chemistry Department, Massachusetts Institute of Technology, Cambridge, MA, USA

  • Center for Environmental Health Sciences, Cambridge, MA, USA

Locations

  • Belgium

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Glioblastoma

Biomarkers

  • N/A

Drug/Treatment

  • Cisplatin

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final

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