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535 : Hydroxychloroquine synergizes with anti-PD-1 immune checkpoint blockade in squamous carcinoma of the head and neck

Researchers

Presenter

  • Avani Vyas

Principal Investigators

  • Silvia Cruz-Rangel

  • Nayel Khan

  • Mikayla Bisignani

  • Lidia Arantes

  • Nicole Schmitt

  • Kirill Kiselyov

  • Robert Ferris

  • Umamaheswar Duvvuri

Medical Centers

  • Emory Department of Otolaryngology, Atlanta, GA, United States

  • Psychiatry, University of Pittsburgh, Pittsburgh, PA, United States

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Solid malignancies

Biomarkers

  • Programmed death-ligand 1

  • Cluster of differentiation 8A

Drug/Treatment

  • Hydroxychloroquine

  • Apilimod mesylate

Outcome

  • N/A

Study Design

  • Randomized

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final

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