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459 : Gene therapy with p19Arf and interferon-beta sensitizes cells to PD-1 checkpoint blockade and enhances antitumor immune responses in resistant mouse models

Researchers

Presenter

  • Ana Domingues

Principal Investigators

  • Nayara Tessarollo

  • Bryan Strauss

Medical Centers

  • Instituto do Cancer do Estado de Sao Paulo - ICESP, Sao Paulo, Brazil

  • Instituto Nacional de Cancer - INCA, Rio De Janeiro, Brazil

  • Universidade Federal de Sao Paulo, Sao Paulo, Brazil

Locations

  • Brazil

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Melanoma

Biomarkers

  • Programmed cell death protein 1

  • Programmed death-ligand 1

Drug/Treatment

  • Interferon Beta

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final

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