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Abstract TP222 : Aging-associated Medin Induces Human Brain Microvascular Endothelial Cell Pro-inflammatory And Pro-thrombotic Activation Partly Via NFκB

Researchers

Presenter

  • Natalie L Nabaty

Principal Investigators

  • Nina Karamanova

  • Seth Truran

  • Kaleb Morrow

  • Robert Schafer

  • Mehdi Nikkhah

  • Ming Li

  • Jillian Madine

  • Raymond Q Migrino

Medical Centers

  • UACOM-P and Phoenix Veterans Affairs, Phoenix, AZ

  • Phoenix Veterens Affairs and UACOM-P, Phoenix, AZ

  • ARIZONA STATE UNIVERSITY, Tempe, AZ

  • Univ of Liverpool, Liverpool

Locations

  • United States

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Pulmonary/Respiratory Diseases

  • Cardiovascular (CVS)

  • Blood/haematological Diseases

Disease

  • Venous thrombosis

Biomarkers

  • Plasminogen activator ihnibitor-1

  • Intercellular adhesion molecule 1

  • Vascular cell adhesion molecule 1

  • Interleukin 6

  • Interleukin-8

Drug/Treatment

  • Thrombomodulin alfa

  • ICAM-1

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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