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: Single and multi-hit PIK3CA short variant (SV) genomic alterations (GA) in clinically advanced prostate cancer (CAPC): A genomic landscape study.

Researchers

Presenter

  • Carla Miguel

Principal Investigators

  • Gennady Bratslavsky

  • Joseph M Jacob

  • Petros Grivas

  • Philippe E. Spiess

  • Andrea Necchi

  • Dean C. Pavlick

  • Richard S.P. Huang

  • Douglas I. Lin

  • Natalie Danziger

  • Ethan Sokol

  • Smruthy Sivakumar

  • Ryon Graf

  • Neil Vasan

  • Jeffrey S. Ross

Medical Centers

  • Department of Medical Oncology, San Raffaele Scientific Institute, Milan, Italy

  • Vita-Salute San Raffaele University,

  • Foundation Medicine, Inc., Boston, MA

  • Department of Medicine, Division of Medical Oncology, University of Washington/ Fred Hutchinson Cancer Research Center, Seattle, WA

  • Upstate Medical University, Syracuse, NY

  • Columbia University Medical Center, New York, NY

  • H. Lee Moffitt Cancer Center & Research Institute, Riverview, FL

Locations

  • Italy

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Urology

Disease

  • Prostate cancer

Biomarkers

  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

  • Programmed death-ligand 1

  • Structural maintenance of chromosomes 4

  • Microsatellite instability

  • Tumor mutational burden

Drug/Treatment

  • Alpelisib

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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