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: Investigation of predictive biomarkers in patients treated with atezolizumab monotherapy following definitive chemoradiotherapy for unresectable locally advanced esophageal squamous cell carcinoma (EPOC1802).

Researchers

Presenter

  • Hideaki Bando

Principal Investigators

  • Daisuke Kotani

  • Saori Mishima

  • Takumi Habu

  • Takahiro Tsushima

  • Hiroki Hara

  • Shigenori Kadowaki

  • Ken Kato

  • Keisho Chin

  • Kensei Yamaguchi

  • Shun-ichiro Kageyama

  • Hidehiro Hojo

  • Masaki Nakamura

  • Tachibana Hidenobu

  • Masashi Wakabayashi

  • Makoto Fukui

  • Nozomu Fuse

  • Hiroyoshi Nishikawa

  • Takashi Kojima

Medical Centers

  • Department of Pharmacy,The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan

  • Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan, Kashiwa, Japan

  • Clinical Research Support Office, National Cancer Center Hospital East, Chiba, Japan

  • Division for the Promotion of Drug and Diagnostic Development, National Cancer Center Hospital East, Kashiwa, Japan

  • Department of Gastroenterology, Chiba Cancer Center, Chiba, Japan

  • Radiation Safety and Quality Assurance division, National Cancer Center Hospital East, Kashiwa, Japan

  • Depertment of Surgical Oncology, National Cancer Center Hospital East, Chiba, Japan

  • Department of Clinical Oncology, Aichi Cancer Center Hospital, Nagoya, Japan

  • Division of Cancer Immunology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center Hospital East, Kashiwa, Japan

  • National Cancer Center Hospital, Tokyo, Japan

  • Division of Gastrointestinal Oncology, Shizuoka Cancer Center, Japan, Shizuoka, Japan

Locations

  • Japan

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Esophageal squamous carcinoma cell

  • Solid malignancies

Biomarkers

  • Programmed death-ligand 1

  • Tissue polypeptide-specific antigen

Drug/Treatment

  • Atezolizumab

Outcome

  • N/A

Study Design

  • Multicenteric

Phase

  • II

Study Id's

  • UMIN000034373

Sponsors

  • N/A

Result

  • N/A

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