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343 : Severe Non-adherence to Hydroxychloroquine Is Associated with Flares, Early Damage, and Mortality in Systemic Lupus Erythematosus: Data from 660 Patients from the Systemic Lupus International Collaborating Clinics (SLICC) Inception Cohort

Researchers

Presenter

  • Yann Nguyen

Principal Investigators

  • Murray Urowitz

  • John Hanly

  • Caroline Gordon

  • Sang-Cheol Bae

  • Juanita Romero-Diaz

  • Jorge Sanchez-Guerrero

  • Ann E Clarke

  • Sasha Bernatsky

  • Daniel Wallace

  • David Isenberg

  • Anisur Rahman

  • Joan Merrill

  • Paul R Fortin

  • Dafna Gladman

  • Ian N. Bruce

  • Michelle Petri

  • Ellen M. Ginzler

  • Mary Anne Dooley

  • Rosalind Ramsey-Goldman

  • Susan Manzi

  • Andreas Jönsen

  • Graciela Alarcón

  • Ronald van Vollenhoven

  • Cynthia Aranow

  • Veronique Le Guern

  • Meggan Mackay

  • Guillermo Ruiz-Irastorza

  • S. Sam Lim

  • Murat Inanc

  • Kenneth C Kalunian

  • Soren Jacobsen

  • Christine Peschken

  • Diane Kamen

  • Anca Askanase

  • Jill Buyon

  • Nathalie Costedoat-Chalumeau

Medical Centers

  • AP-HP.Centre Universit Paris Cit Hôpital Cochin, Montmorency, France

  • Biologie du médicament-Toxicologie, AP-HP Centre – Hôpital Cochin, Université Paris Cité, Paris, France, Paris

  • University of Toronto, University Health Network, Schroeder Arthritis Institute, Toronto, ON, Canada

  • Division of Rheumatology, Queen Elizabeth II Health Sciences Center (Nova Scotia Rehabilitation Site) and Dalhousie University, Halifax, NS, Canada

  • Institute of Inflammation and Ageing College of Medical and Dental Sciences University of Birmingham, Birmingham, United Kingdom

  • Hanyang University Medical Center, Seoul, Republic of Korea

  • Instituto Nacional de Ciencias Medicas y Nutricion, Mexico City, Mexico

  • Mount Sinai Hospital and University Health Network, University of Toronto, Canada, Toronto, ON, Canada

  • University of Calgary, Division of Rheumatology, Cumming School of Medicine, Calgary, AB, Canada

  • Research Institute McGill University Health Center, Montreal, Quebec, Canada

  • Cedars-Sinai Medical Center, Los Angeles, CA

  • Kings College London, London, United Kingdom

  • Centre for Haematology, Department of Medicine, Imperial College London, London, United Kingdom

  • Oklahoma Medical Research Foundation, Oklahoma city, OK.

  • Centre de Recherche ARThrite, CHU de Québec - Université Laval, Québec, QC, Canada

  • Toronto Western Hospital, Schroeder Arthritis Institute, Toronto, Canada

  • Centre for Epidemiology Versus Arthritis, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom

  • Johns Hopkins University School of Medicine, Devision of Rheumatology, Baltimore, MD

  • SUNY Downstate Health Sciences University, Department of Medicine, Brooklyn, NY

  • Injury Prevention Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC

  • Northwestern University, Feinberg School of Medicine, Chicago, IL

  • Allegheny Health Network, Lupus Center of Excellence, Wexford, PA

  • Lund University Hospital, Lund, Sweden

  • The University of Alabama at Birmingham, Oakland

  • VU University Medical Center, Amsterdam, Netherlands

  • Feinstein Institute for Medical Research, Manhasset, NY

  • Hopital Cochin, Paris, France

  • Autoimmune Diseases Research Unit, Biocruces Bizkaia Health Research Institute, Hospital Universitario Cruces, UPV/EHU, Barakaldo, Spain

  • Emory University, Atlanta, GA

  • Rheumatology, Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey

  • University of California, San Diego School of Medicine, La Jolla, CA

  • Rigshospitalet, Copenhagen, Denmark

  • Faculty of Medicine, University of Manitoba, Winnipeg, MB, Canada

  • Medcl Univ of South Carolina, Charleston, SC

  • Columbia University Medical Center, New York, NY

  • Icahn School of Medicine, New York, NY

  • Inserm DR Paris 5, Paris, France

Locations

  • United States

  • France

  • Canada

  • United Kingdom

  • Republic of South Korea

  • Mexico

  • Sweden

  • Netherlands

  • Spain

  • Turkey

  • Denmark

Companies

  • N/A

Study Components

Therapeutic Area

  • Nephrology

  • Autoimmune (AI)

Disease

  • Lupus

  • Nephrotic syndrome

  • Nephritis

Biomarkers

  • Albumin/creatinine

Drug/Treatment

  • Hydroxychloroquine

  • Prednisone

Outcome

  • N/A

Study Design

  • Multinational

  • Multicenteric

  • Prospective

  • Cohort

Phase

  • N/A

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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