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510 : MACE and VTE Across Upadacitinib Clinical Trial Programs in Rheumatoid Arthritis, Psoriatic Arthritis, and Ankylosing Spondylitis

Researchers

Presenter

  • Christina Charles-Schoeman

Principal Investigators

  • Ernest Choy

  • Iain B McInnes

  • Eduardo Mysler

  • Peter Nash

  • Kunihiro Yamaoka

  • Ralph Lippe

  • Nasser Khan

  • Anna K Shmagel

  • Hannah Palac

  • Jessica Suboticki

  • Jeffrey Curtis

Medical Centers

  • Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow, United Kingdom

  • Division of Infection and Immunity, Cardiff University, Cardiff, United Kingdom

  • School of Medicine, Griffith University, QLD, Australia, Brisbane, Australia

  • Division of Hematoogy/Oncology, University of California, Los Angeles, Santa Monica, CA

  • Department of Rheumatology, OMI (Medical Research Organization), Buenos Aires, Argentina

  • Rheumatology and Infectious Diseases, Kitasato University School of Medicine, Kanagawa, Japan

  • Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL

  • AbbVie, Inc, Wiesbaden, Germany

Locations

  • Russia

  • United States

  • United Kingdom

  • Argentina

  • Australia

  • Japan

  • Germany

Companies

  • N/A

Study Components

Therapeutic Area

  • Autoimmune (AI)

  • Musculoskeletal

  • Pulmonary/Respiratory Diseases

  • Central Nervous System (CNS)

  • Cardiovascular (CVS)

  • Dermatology

  • Blood/haematological Diseases

Disease

  • Ankylosing spondylitis

  • Myocardial infarction

  • Rheumatoid arthritis

  • Deep vein thrombosis

  • Psoriatic arthritis

  • Pulmonary embolism

  • Venous thrombosis

  • Inflammatory Arthritis

  • Stroke

Biomarkers

  • Plasminogen Activator, Urokinase

Drug/Treatment

  • ABT-494

  • Adalimumab

Outcome

  • N/A

Study Design

  • Randomized

  • Double Blind/Blinded

  • Controlled

Phase

  • II

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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