// App-Quantinova.ai

5571 : Disruption of cell-intrinsic checkpoint regulator CTLA-4 in CD19 directed CAR T cells provides clinical efficacy in CLL patients

Researchers

Presenter

  • Sangya Agarwal

Principal Investigators

  • Angela Aznar M. Gomez

  • Tong Da

  • Shunichiro Kuramitsu

  • Weimin Kong

  • Pranali Ravikumar

  • Mercy Gohil

  • Megan M. Davis

  • Joseph A. Fraietta

  • Gabriela Plesa

  • David L. Porter

  • Regina M. Young

  • Carl H. June

Medical Centers

  • University of Pennsylvania, Philadelphia, PA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Chronic Lymphocytic Leukemia

  • Lymphomas

  • Solid malignancies

Biomarkers

  • Breakpoint Cluster Region

  • Coxsackie Virus And Adenovirus Receptor

  • Cluster of Differentiation 19

  • Programmed cell death protein 1

  • Cytotoxic T-lymphocyte-associated protein 4

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

Copyright © 2026. QuantiNova All rights reserved