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S105 : IN VIVO PDX CRISPR/CAS9 SCREENS REVEAL MUTUAL THERAPEUTIC TARGETS TO OVERCOME HETEROGENEOUS ACQUIRED CHEMO-RESISTANCE

Researchers

Presenter

  • Anna-Katharina Wirth

Principal Investigators

  • Lucas Wange

  • Sebastian Vosberg

  • Ashok Kumar Jayavelu

  • Wolfgang Enard

  • Tobias Herold

  • Irmela Jeremias

Medical Centers

  • Department of Medicine III, and Laborat

  • Clinical Division of Oncology, Department of Internal Medicine,Medical University of Graz,Graz,Österreich

  • Apoptosis in Hematopoietic stem cells,Helmholtz Zentrum München, German Research Center for Environmental Health (HMGU),Muni

  • Department of Medicine III, and Laboratory for Leukemia Diagnostics,Ludwig Maximilian University (LMU),Munich,Allemagne

  • Anthropology and Human Genomics, Faculty of Biology,Ludwig Maximilian Un

  • Department of Medicine III, and Laboratory for Leukemia Diagnostics,Ludwig Maximilian University (LMU),Munich,Allemagne

  • Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry,

  • Division of Oncology, Department of Internal Medicine, Korea University Anam...

  • Anthropology and Human Genomics, Faculty of Biology,Ludwig Maximilian University (LMU),Martinsried,Germania

  • Anthropology and Human Genomics, Faculty of Biology,Ludwig Maximilian University (LMU),Martinsried,Germania

  • Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry,

  • Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry,

  • Clinical Division of Oncology, Department of Internal Medicine,Medical University of Graz,Graz,Österreich

  • Apoptosis in Hematopoietic stem cells,Helmholtz Zentrum München, German Research Center for Environmental Health (HMGU),Muni

  • Apoptosis in Hematopoietic stem cells,Helmholtz Zentrum München, German Research Center for Environmental Health (HMGU),Muni

  • Division of Clinical Oncology, Department of Internal Medicine, Medical University Graz, Graz, Austria

  • Department of Medicine III, and Laboratory for Leukemia Diagnostics,Ludwig Maximilian University (LMU),Munich,Allemagne

  • Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry,

  • Anthropology and Human Genomics, Faculty of Biology,Ludwig Maximilian University (LMU),Martinsried,Germania

Locations

  • Germany

  • United States

  • India

  • Austria

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

Biomarkers

  • Breakpoint Cluster Region

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • N/A

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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