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POS0462 (2022) : HYDROXYCHLOROQUINE REDUCES THE TITERS OF ANTI-DOMAIN 1 ANTIBODIES OVER TIME IN PATIENTS WITH PERSISTENTLY POSITIVE ANTIPHOSPHOLIPID ANTIBODIES: RESULTS FROM THE APS ACTION CLINICAL DATABASE AND REPOSITORY (“REGISTRY”)

Researchers

Presenter

  • C. Chighizola

Principal Investigators

  • D. Andrade

  • M. Tektonidou

  • S. Sciascia

  • V. Pengo

  • A. Ugarte

  • H. M. Belmont

  • M. Gerosa

  • P. Fortin

  • C. Lopez-Pedrera

  • Z. Zhang

  • T. Atsumi

  • G. De Jess

  • N. Kello

  • D. W. Branch

  • L. Andreoli

  • D. Wahl

  • M. A. Petri

  • E. Rodrguez Almaraz

  • R. Cervera

  • G. Pons Estel

  • J. Knight

  • R. Willis

  • M. Barber

  • B. Artim Esen

  • M. Efthymiou

  • D. Erkan

  • M. L. Bertolaccini

Medical Centers

  • University of Milan, Pediatric Rheumatology Unit, ASST G. Pini - CTO, Milan, Italy

  • University of Sao Paulo, Rheumatology Division, Sao Paulo, Brazil

  • National and Kapodistrian University of Athens, First Department of Propaedeutic and Internal Medicine, Laiko Hospital, Athens, Greece

  • University of Turin, Clinical and Biological Sciences, Torino, Italy

  • University of Padova, Department of Cardiac, Thoracic and Vascular Sciences, Padova, Italy

  • Universidad del País Vasco/Euskal Herriko Unibertsitatea, Unidad de Investigación de Enfermedades Autoinmunes, Servicio de Medicina Interna, BioCruces Health Research Institute, Hospital Universitario Cruces, Barakaldo, Spain

  • New York University Hospital for Joint Diseases, New York, New York, United States

  • University of Milan, Clinical Rheumatology Unit, Milan, Italy

  • Université Laval, Medicine, Quebec, Canada

  • University of Cordoba, ‘Systemic autoimmune diseases and chronic arthropathies’ IMIBIC-Reina Sofia Hospital, Cordoba, Spain

  • Peking University First Hospital, Rheumatology and Immunology department, Beijing, China

  • Hokkaido University, Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Sapporo, Japan

  • Universidade do Estado do Rio de Janeiro, Department of Obstetrics, Rio de Janeiro, Brazil

  • Northwell Health, Division of Rheumatology, Great Neck, United States of America

  • University of Utah and Intermountain Healthcare, Department of Obstetrics, Salt Lake City, United States of America

  • University of Pisa, Gastroenterology Unit, Pisa, Italy

  • Nancy University, Internal Medicine, Nancy, France

  • The Johns Hopkins University, Baltimore, United States of America

  • Hospital Clinic de Barcelona, Autoimmune Diseases, Barcelona, Spain

  • Centro Regional de Enfermedades Autoinmunes y Reumáticas (CREAR), Grupo Oroño,Rosario, Rosario, Argentina

  • University of Michigan, Division of Rheumatology, Ann Arbor, United States of America

  • University of Texas Medical Branch, Internal Medicine, Galveston, USA

  • University of Calgary, Division of Hematology, Calgary, AB, Canada

  • University of Istanbul, Division of Rheumatology, Istanbul, Turkey

  • University College London Hospital, Department of Pathology, London, United Kingdom

  • Hospital for Special Surgery Main Hospital, New York, United States of America

  • King’s College London, Vascular Risk and Surgery Section, London, United Kingdom

Locations

  • Italy

  • Brazil

  • Greece

  • Spain

  • United States

  • Canada

  • China

  • Japan

  • France

  • Argentina

  • Turkey

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Autoimmune (AI)

Disease

  • Antiphospholipid syndrome

Biomarkers

  • Glycosylphosphatidylinositol

  • Immunoglobulin G

Drug/Treatment

  • Hydroxychloroquine

Outcome

  • N/A

Study Design

  • Multinational

Phase

  • N/A

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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