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OP0058 (2022) : CERTOLIZUMAB-PEGOL, ABATACEPT, TOCILIZUMAB OR ACTIVE CONVENTIONAL THERAPY IN EARLY RHEUMATOID ARTHRITIS: CLINICAL AND RADIOGRAPHIC 48-WEEKS RESULTS OF THE INVESTIGATOR-INITIATED RANDOMIZED NORD-STAR TRIAL

Researchers

Presenter

  • M. stergaard

Principal Investigators

  • A. Rudin

  • M. L. Hetland

  • M. Heiberg

  • D. Nordstrm

  • M. Nurmohamed

  • B. Gudbjornsson

  • L. Midtbll rnbjerg

  • P. Byesen

  • I. Olsen

  • K. Lend

  • K. Hrslev-Petersen

  • T. Uhlig

  • T. Sokka-Isler

  • G. Grndal

  • S. Krabbe

  • J. Lindqvist

  • I. Gjertsson

  • D. Glinatsi

  • M. C. Kapetanovic

  • A. B. Aga

  • F. Faustini

  • P. Parmanne

  • T. Lorenzen

  • G. Cagnotto

  • J. Back

  • O. Hendricks

  • D. Vedder

  • T. Rannio

  • E. Grenholm

  • H. M. Lindegaard

  • M. K. A. Ljosa

  • E. Brodin

  • A. Soderbergh

  • M. Rizk

  • E. Hermansson

  • L. Uhrenholt

  • P. Larsson

  • S. A. Just

  • G. Bakland

  • D. Stevens

  • T. B. Laurberg

  • E. A. Haavardsholm

  • J. Lampa

Medical Centers

  • Amsterdam University Medical Center, Amsterdam Rheumatology Center, Amsterdam, Netherlands

  • Sahlgrenska University Hospital, Rheumatology clinic, Göteborg, Sweden

  • Rigshospitalet, Glostrup, DANBIO and COPECARE, Centre for Rheumatology and Spine Diseases, Glostrup, Denmark

  • Diakonhjemmet Hospital, Rheumatology Unit, Oslo, Norway

  • Amsterdam University Medical Center - Amsterdam - Netherlands (The)

  • University of Iceland, Dept of Rheumatology, Reykjavik, Iceland

  • Oslo University Hospital, Dept of Research Support for Clinical Trials, Oslo, Norway

  • Amsterdam University Medical Center/Karolinska Institute, Dept of Rheumatology and Amsterdam Rheumatology Center/Center for Molecular Medicine, Amsterdam, Netherlands

  • Kong Chr X’s Hospital for Rheumatic Diseases, Dept of Rheumatology, Gråsten, Denmark

  • University of Eastern Finland, Dept of Rheumatology, Jyväskylä, Finland

  • Herlev University Hospital, Dept. of Cardiology, Herlev, Denmark

  • Karolinska University Hospital, Dept of Medicine, Rheumatology Unit, Center of Molecular Medicine (CMM), Stockholm, Sweden

  • Sahlgrenska University Hospital, Division of Rheumatology, Goteborg, Sweden

  • Skåne University Hospital, Dept of Clinical Sciences, Malmö, Sweden

  • Karolinska University Hospital, Department of Medicine, Unit of Rheumatology, Stockholm, Stockholm, Sweden

  • Silkeborg University Hospital, Dept of Rheumatology, Silkeborg, Denmark

  • Skåne University Hospital, Dept of Clinical Sciences, Malmö, Sweden

  • Uppsala University, Department of Medical Sciences, Uppsala, Sweden

  • Danish Hospital for Rheumatic Diseases, Department of Rheumatology, Sønderborg, Denmark

  • Finland Central Hospital, Dept of Rheumatology, Jyväskylä, Finland

  • Falun Hospital, Dept of Rheumatology, Falun, Sweden

  • Odense University Hospital, Hematological Research Unit, Odense, Denmark

  • Alesund Hospital, Rheumatology, Ålesund, Norway

  • Haukeland University Hospital, Dept of Rheumatology, Haukeland, Norway

  • Örebro University Hospital, Dept of Rheumatology, Örebro, Sweden

  • Värmlands Hospital, Rheumatology Clinic, Västerås, Sweden

  • Linkoping University Hospital, Department of Hematology, Linkoping, Sweden

  • Aalborg University hospital, Department of Rheumatology, Aalborg, Denmark

  • Academic specialist center. Stockholm, Center for Rheumatology, Stockholm, Sweden

  • Odense University Hospital, Svendborg, Medicine, Section of Rheumatology, Svendborg, Denmark

  • University Hospital of North Norway, Dept of Rheumatology, North Norway, Norway

  • University Hospital of Trondheim, Dept of Rheumatology, Trondheim, Norway

  • Aarhus University Hospital, Rheumatology, Århus N, Denmark

  • Karolinska University Hospital, Rheumatology Unit, Stockholm, Sweden

Locations

  • Denmark

  • Netherlands

  • Sweden

  • Norway

  • Finland

  • Iceland

Companies

  • N/A

Study Components

Therapeutic Area

  • Genetic Disorder

  • Autoimmune (AI)

Disease

  • Rheumatoid arthritis

  • STAR syndrome

Biomarkers

  • anti-CCP antibodies

  • C reactive protein

Drug/Treatment

  • Certolizumab pegol

  • Hydroxychloroquine

  • sulphasalazine

  • Glucocorticoid

  • Methotrexate

  • Prednisolone

  • Tocilizumab

  • Abatacept

Outcome

  • N/A

Study Design

  • Randomized

  • Double Blind/Blinded

  • Open Label

Phase

  • N/A

Study Id's

  • NCT01491815

Sponsors

  • Abbvie

Result

  • N/A

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