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: Combined inhibition of JAK/STAT and BCL2 during ex vivo NK cell expansion enriches a highly cytotoxic NK cell subset

Researchers

Presenter

  • Kirsti Lorraine Walker

Principal Investigators

  • Tara B Gavcovich

  • Dennis Ea

  • Christian M. Capitini

Medical Centers

  • Univ. of wisconsin-madison

  • George Washington Univ.

  • UW Carbone Cancer Center

Locations

  • N/A

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • T-cell acute lymphoblastic leukemia

Biomarkers

  • Natural Killer cells

  • B-cell lymphoma 2

  • Cluster of Differentiation 56

  • Cluster of differentiation 69

  • Programmed cell death protein 1

  • Fc gamma RIIIa

  • Interleukin-15

  • Janus kinase

  • Signal Transducer And Activator Of Transcription 1

Drug/Treatment

  • Ruxolitinib phosphate

  • Venetoclax

  • IL-15

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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