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: Vincristine Induced Peripheral Neuropathy: A Randomized Controlled Trial Comparing Bolus Injections with One Hour Infusions during Induction in a Pediatric Population of Acute Lymphoblastic Leukemia and Hodgkin's Lymphoma

Researchers

Presenter

  • Mirjam Esther Velde

Principal Investigators

  • Machteld Heleen van den Berg

  • Floor Abbink

  • Heidi Segers

  • Barbara De Moerloose

  • Marry M. van den Heuvel-Eibrink

  • Cor van den Bos

  • Inge M. van der Sluis

  • Gertjan Johannes Laurentius Kaspers

Medical Centers

  • VUmc, Department of Pediatric Oncology, Amsterdam UMC/Emma Children's Hospital, Amsterdam, Netherlands

  • VUmc, Department of Pediatric Oncology, Amsterdam UMC/Emma Children's Hospital, Amsterdam, Netherlands

  • Department of General Medical Oncology, University Hospitals Leuven, Leuven, Belgium

  • Department of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, Ghent, Belgium

  • Princess Maxima Center for Pediatric Oncology, Netherlands

  • VUmc Amsterdam, Emma Children's Hospital, Department of Pediatric Hematology/Oncology, VU University Medical Center, Amsterdam, Netherlands

Locations

  • Netherlands

  • Belgium

Companies

  • N/A

Study Components

Therapeutic Area

  • Endocrine/metabolic Diseases (ME)

  • Peripheral Nervous System

  • Gastroenterology (GU)

  • Oncology (ONC)

  • Genetic Disorder

Disease

  • Peripheral neuropathy

  • Acute lymphoblastic leukemia

  • Hodgkin's Lymphoma

  • Mismatch repair deficiency

  • Constipation

  • Lymphomas

  • Solid malignancies

Biomarkers

  • Breakpoint Cluster Region

  • Purine nucleoside phosphorylase

Drug/Treatment

  • Vincristine

Outcome

  • N/A

Study Design

  • Randomized

  • Multinational

  • Controlled

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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