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: ARRB1-Induced NOTCH1 Degradation Is Inhibited By Mir-223 in T-ALL

Researchers

Presenter

  • Lin Zou

Principal Investigators

  • Yi Wang

  • Wenqiong Lv

  • Danyi Peng

  • Hang Zhang

  • Guangjie Jiang

  • Shan Liu

  • Yanhua Chen

  • Shi Tang

  • Guo Fu

  • Xinkun Qi

  • Zhidai Liu

  • Haiyan Liu

  • Chao Yang

  • Fangjie Liu

  • Jie Yu

  • Penghui Zhang

  • Bin Qu

  • Hui Zhao

  • Tongchuan He

Medical Centers

  • Chongqing Medical University, Chongqing, China

  • Saarland University, Homburg, Germany.

  • The Chinese University of Hong Kong, Hong Kong, Hong Kong

  • The University of Chicago Medical Center, Chicago, IL

Locations

  • China

  • Germany

Companies

  • N/A

Study Components

Therapeutic Area

  • Central Nervous System (CNS)

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Chronic Myelogenous Leukemia

  • Acute myelocytic leukemia

  • Solid malignancies

  • T-cell acute lymphoblastic leukemia

  • B-cell acute lymphoblastic leukemia

  • Lung disease, immunodeficiency, and chromosome breakage syndrome

Biomarkers

  • Neurogenic locus notch homolog protein 1

  • Breakpoint Cluster Region

  • Phosphatase and tensin homolog

  • DNA methyltransferase 1

  • Enhancer of zeste homolog 2

  • Telomerase reverse transcriptase

Drug/Treatment

  • EZH2

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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