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: Contribution of Amino Acid Metabolism to Hematologic Malignancies

Researchers

Presenter

  • Marina Y. Konopleva

Principal Investigators

  • Philip L Lorenzi

  • Sanaz Ghotbaldini

  • Yoko Tabe

  • Tianyu Cai

  • Stefano Tiziani

Medical Centers

  • Department of Bioinformatics, The University of Texas MD Anderson Cancer Center, Houston, TX

  • Department of Bioinformatics, The University of Texas MD Anderson Cancer Center, Houston, TX

  • 1.MD Anderson Cancer Center, Houston, TX

  • Department of Respiratory Medicine, Juntendo University School of Medicine, Tokyo, Japan

  • Department of Bioinformatics, The University of Texas MD Anderson Cancer Center, Houston, TX

  • The University of Texas at Austin, Austin, TX

Locations

  • United States

  • Japan

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Infectious Diseases (ID)

Disease

  • Chronic Lymphocytic Leukemia

  • Acute lymphoblastic leukemia

  • Hematological malignancies

  • Acute myelocytic leukemia

  • Multiple Myeloma

  • Solid malignancies

  • Tuberculosis

  • Lymphomas

Biomarkers

  • Abelson murine leukemia viral oncogene homolog 2

  • Argininosuccinate Synthase 1

  • B-cell lymphoma 2

Drug/Treatment

  • Asparaginase

  • PEG-arginase

  • Proglumide

  • glutathione

  • Pegargiminase

  • Glutamine

  • Arginine hydrochloride

  • Cysteine Hydrochloride

  • L-Tyrosine

Outcome

  • N/A

Study Design

  • N/A

Phase

  • I/II

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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