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: A Novel Approach to Identifying Septic Shock (SS) in Children with Acute Lymphoblastic Leukemia (ALL) Using Pediatric Health Information System (PHIS) Data: Methods Validation and Incidence Estimation in a National Cohort

Researchers

Presenter

  • Viviane C. Cahen

Principal Investigators

  • Yimei Li

  • Evanette Burrows

  • Caitlin W Elgarten

  • Amanda M. DiNofia

  • Jennifer J. Wilkes

  • Lena E. Winestone

  • Yuan-Shung V. Huang

  • Julie C Fitzgerald

  • M. Monica Gramatges

  • Karen R. Rabin

  • Brian T. Fisher

  • Kelly D Getz

  • Richard Aplenc

  • Alix E. Seif

Medical Centers

  • Center for Childhood Cancer Research, Childrens Hospital of Philadelphia, Philadelphia, PA

  • Department of Biomedical and Health Informatics, The Childrens Hospital of Philadelphia, Philadelphia, PA

  • Department of Pathology, The Children's Hospital of Philadelphia, Philadelphia, PA

  • Department of Pediatrics, University of Washington, Division of Hematology/Oncology, Seattle Children's Hospital, Seattle, WA

  • Division of Allergy, Immunology, and BMT, UCSF Benioff Children's Hospital, San Francisco, CA

  • Center for Pediatric Clinical Effectiveness, The Childrens Hospital of Philadelphia, Philadelphia, PA

  • Anesthesia and Critical Care Medicine, The Childrens Hospital of Philadelphia, Philadelphia, PA

  • Department of Pediatrics, Baylor College of Medicine, Division of Hematology-Oncology, Texas Children's Hospital, Houston, TX

  • Division of Hematology-Oncology, Texas Children's Hospital, Department of Pediatrics, Baylor College of Medicine, Houston, TX

  • Division of Infectious Diseases, Children's Hospital of Philadelphia, Philadelphia, PA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Infectious Diseases (ID)

  • Blood/haematological Diseases

  • Autoimmune (AI)

Disease

  • Acute lymphoblastic leukemia

  • Septic shock

  • Anaphylaxis

  • Sepsis

Biomarkers

  • Breakpoint Cluster Region

  • DNA Damage Inducible Transcript 3

  • Interferon Regulatory Factor 1

Drug/Treatment

  • Daunorubicin

  • Asparaginase

  • Epinephrine

  • Adrenaclick

Outcome

  • N/A

Study Design

  • Multinational

  • Cohort

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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