// App-Quantinova.ai

: Inhibition of Unc-51-like Kinase 1 (ULK1) with Novel Small Molecular Inhibitor MRT68921 Preferentially Induces Apoptosis and Autophagy in FLT3-ITD- Mutated Acute Myeloid Leukemia

Researchers

Presenter

  • Jieun Jang

Principal Investigators

  • Hoi-kyung Jeung

  • So-Young Seol

  • Haerim Chung

  • Yu Ri Kim

  • June-Won Cheong

  • Yoo Hong Min

Medical Centers

  • Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea, Republic of.

  • Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Korea, Republic of (South)

Locations

  • Republic of South Korea

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute myelocytic leukemia

Biomarkers

  • Phosphorylated signal transducer and activator of transcription 5

  • L-serine

Drug/Treatment

  • Hydroxychloroquine

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

Copyright © 2026. QuantiNova All rights reserved