// App-Quantinova.ai

: Vector Integration and Efficacy of CD19-Directed CAR T Cell Therapy in Acute Lymphoblastic Leukemia (ALL) and Chronic Lymphocytic Leukemia (CLL)

Researchers

Presenter

  • Christopher L Nobles

Principal Investigators

  • John K Everett

  • Shantan Reddy

  • Joseph A Fraietta

  • David L. Porter

  • Noelle V. Frey

  • Stephan A. Grupp

  • Don L. Siegel

  • Simon F Lacey

  • Carl H June

  • Frederic D Bushman

  • J. Joseph Melenhorst

Medical Centers

  • Department of Medicine, University of Pennsylvania, Philadelphia, PA

  • University of Pennsylvania, Philadelphia, PA

  • Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA

  • Division of Hematology/Oncology, Abramson Cancer Center of the University of Pennsylvania, Philadelphia, PA

  • Division of Hematology-Oncology, Department of Medicine, University of Pennsylvania, Merion Station, PA

  • Center for Childhood Cancer Research, Childrens Hospital of Philadelphia, Philadelphia, PA

  • Center for Cellular Immunotherapies, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA

  • Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, PA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Chronic Lymphocytic Leukemia

  • Solid malignancies

Biomarkers

  • Breakpoint Cluster Region

  • Tet methylcytosine dioxygenase 2

Drug/Treatment

  • CTL019

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

Copyright © 2026. QuantiNova All rights reserved