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: A Critical Role of Growth Arrest-Specific Gene 6-Mer Axis in the Pathogenesis of Endothelial Damage Contributing to Thrombotic Microangiopathy Associated with Graft-Versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation

Researchers

Presenter

  • Miki Furukawa

Principal Investigators

  • Wang Xintao

  • Hiroshi Ohkawara

  • Masahiko Fukatsu

  • Lobna Alkebsi

  • Hideyoshi Noji

  • Kazuei Ogawa

  • Takayuki Ikezoe

Medical Centers

  • Hakozaki, Date, Fukushima, Japan, Kita-Fukushima Medical Center, Date, Japan

  • Department of Chest Surgery, Fukushima Medical University, Fukushima, Japan

  • Department of Pediatric Oncology, Fukushima Medical University, Fukushima, Japan

  • Dept. of Medical Oncology, Fukushima Medical University School of Medicine, Fukushima, Japan

Locations

  • Japan

Companies

  • N/A

Study Components

Therapeutic Area

  • Autoimmune (AI)

  • Cardiovascular (CVS)

  • Blood/haematological Diseases

  • Pulmonary/Respiratory Diseases

  • Musculoskeletal

Disease

  • Thrombotic microangiopathy

  • Graft-versus-host disease

  • Vasodilation dysfunction

  • Venous thrombosis

Biomarkers

  • Plasminogen activator ihnibitor-1

  • D-dimer

  • Intercellular adhesion molecule 1

  • Vascular cell adhesion molecule 1

Drug/Treatment

  • Thrombomodulin alfa

  • Hemostatic Solution

  • Protein C

  • folitixorin calcium

  • L-Tyrosine

  • ICAM-1

  • ribose

  • Allopurinol

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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