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: Genomic Analysis of Myelodysplastic Syndromes Among Nagasaki Atomic Bomb Survivors

Researchers

Presenter

  • Masataka Taguchi

Principal Investigators

  • Yusuke Shiozawa

  • Chisa Hayashida

  • Akira Kinoshita

  • Shinya Sato

  • Makiko Horai

  • Masatoshi Matsuo

  • Hidehiro Itonaga

  • Takeharu Kato

  • Hiroaki Taniguchi

  • Daisuke Imanishi

  • Yoshitaka Imaizumi

  • Tomoko Hata

  • Motoi Takenaka

  • Hideki Makishima

  • Yasuhito Nannya

  • Yukiyoshi Moriuchi

  • Seishi Ogawa

  • Koh-ichiro Yoshiura

  • Yasushi Miyazaki

Medical Centers

  • Department of Hematology and Molecular Medicine Unit, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan

  • Department of Hematology and Molecular Medicine Unit, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan

  • Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan

  • Department of Hematology, Sasebo City General Hospital, Sasebo, Japan

  • Department of Surgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan

  • Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan

  • Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, Kyoto, Japan

Locations

  • Japan

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Myelodysplastic Syndrome

  • Chronic Myelogenous Leukemia

  • Acute myelocytic leukemia

  • Solid malignancies

Biomarkers

  • E3 ubiquitin-protein ligase CBL

  • Histone-lysine N-methyltransferase 2A

  • Tet methylcytosine dioxygenase 2

  • Tumor protein p53

  • Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Epsilon

  • DNA methylation

  • Ataxia-telangiectasia mutated

Drug/Treatment

  • TP53

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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