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: Glucocorticoid Resistance in IKZF1-Deleted BCP-ALL: It Is PTEN Again

Researchers

Presenter

  • Laurens Van Der Meer

Principal Investigators

  • Rene Marke

  • Miriam Butler

  • Dorette van Ingen Schenau

  • Blanca Scheijen

  • Frank van Leeuwen

Medical Centers

  • Princess Maxima Center for Pediatric Oncology, Netherlands

  • Laboratory of Pediatric Oncology, Radboudumc, Nijmegen, Netherlands

  • Princess Maxima Center for Pediatric Oncology, Netherlands

  • Rheumatology, Radboudumc, Nijmegen, Netherlands

Locations

  • Netherlands

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Genetic Disorder

Disease

  • Acute lymphoblastic leukemia

  • Glucocorticoid resistance

  • T-cell acute lymphoblastic leukemia

Biomarkers

  • Phosphatase and tensin homolog

  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

  • Phosphorylated-AKT

  • Mesenchymal stem cells

  • Telomerase reverse transcriptase

Drug/Treatment

  • Glucocorticoid

  • Prednisolone

  • Prednisone

  • MK 2206

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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