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: PIM Inhibitor SMI-4a Induces Cell Apoptosis and Cell Cycle Arrest in B-Cell Acute Lymphocytic Leukemia Cells Via the JAK2/STAT3 Pathway

Researchers

Presenter

  • Xingyi Kuang

Principal Investigators

  • Jie Xiong

  • Weili Wang

  • Xinyao Li

  • Tingting Lu

  • Jishi Wang

Medical Centers

  • Affiliated Hospital of Guilin Medical University, Guilin, China

  • Affiliated Hospital of Guilin Medical University, Guilin, China

  • Affiliated Hospital of Guilin Medical University, Guilin, China

  • Affiliated Cancer Hospital & Institute, Guangzhou Medical University, Guangzhou, China

Locations

  • China

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Genetic Disorder

Disease

  • Acute lymphoblastic leukemia

  • Hematological malignancies

  • B-cell acute lymphoblastic leukemia

  • Heme oxygenase 1 deficiency

Biomarkers

  • B-cell lymphoma 2

  • Cyclin dependent kinase inhibitor 1A

  • Caspase 3

  • Cyclin-dependent kinase 4

  • Heme oxygenase-1

  • Signal transducer and activator of transcription 3

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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