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: Comprehensive Genomic Analysis Identified Acute Lymphoblastic Leukemia in Down Syndrome Was Highly Heterogeneous with the High Prevalence of Ph-like Signature

Researchers

Presenter

  • Yasuo Kubota

Principal Investigators

  • Kumiko Uryu

  • Tatsuya Ito

  • Masafumi Seki

  • Tomoya Isobe

  • Tsutomu Toki

  • Kenichi Yoshida

  • Yuichi Shiraishi

  • Kenichi Chiba

  • Hiroko Tanaka

  • MItsuteru Hiwatari

  • Satoru Miyano

  • Akira Oka

  • Seishi Ogawa

  • Kiminori Terui

  • Atsushi Sato

  • Etsuro Ito

  • Junko Takita

Medical Centers

  • Department of Biostatistics, The University of Tokyo, Tokyo, Japan

  • Department of Gastroenterological Surgery, Hirosaki University Graduate School of Medicine, Hirosaki, Japan

  • Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan

  • Laboratory of DNA information Analysis, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan

  • Department of Cell Therapy and Transplantation Medicine, The University of Tokyo Hospital, Tokyo, Japan

  • Department of Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, Kyoto, Japan

  • Department of Medicine, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Huddinge, Sweden

  • Miyagi Children's Hospital, Sendai, Japan

Locations

  • Japan

  • Sweden

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Genetic Disorder

Disease

  • Acute lymphoblastic leukemia

  • Down syndrome

Biomarkers

  • ETV6-RUNX1

Drug/Treatment

  • N/A

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A