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: Functional and Genomic Characterization of the Interaction between Acute Lymphoblastic Leukemia Cells and the Microenvironment Identifies Pathways for Therapeutic Intervention

Researchers

Presenter

  • Hiroki Yoshihara

Principal Investigators

  • Michelle L. Churchman

  • Jennifer L. Peters

  • David B. Finkelstein

  • Elisabeth M. Paietta

  • Mark R. Litzow

  • Charles G. Mullighan

Medical Centers

  • Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN

  • Cell & Tissue Imaging Center, St. Jude Children's Research Hospital, Memphis, TN

  • Computational Biology, St Jude Children's Research Hospital, Memphis, TN

  • Department of Medical Oncology, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY

  • Division of Medical Oncology, Mayo Clinic, Rochester, MN

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

Biomarkers

  • Breakpoint Cluster Region

  • Cluster of Differentiation 19

  • ETS transcription factor ERG

  • ETV6-RUNX1

  • Mesenchymal stem cells

  • Telomerase reverse transcriptase

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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