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: Genome Wide Association Analyses Identify Pleiotropic Variants Associated with Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) Susceptibility

Researchers

Presenter

  • Junke Wang

Principal Investigators

  • Ezgi Karaesmen

  • Abbas Rizvi

  • Qianqian Zhu

  • Li Yan

  • Leah Preus

  • Song Liu

  • Daniel Stram

  • Loreall Pooler

  • Xin Cheng

  • Christopher Haiman

  • David Van Den Berg

  • Amy Webb

  • Guy Brock

  • Elizabeth A. Griffiths

  • Stephen R. Spellman

  • Marcelo C Pasquini

  • Philip L. McCarthy

  • James M. Allan

  • Kenan Onel

  • Theresa E. Hahn

  • Lara E. Sucheston-Campbell

Medical Centers

  • College of Medicine, The Ohio State University, Columbus, OH

  • Mayo Clinic, Rochester, MN

  • Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY

  • Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA

  • Department of Pediatrics, University of Southern California Keck School of Medicine, Los Angeles, CA

  • Department of Biomedical Informatics, The Ohio State University, Columbus, OH

  • Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY

  • CIBMTR (Center for International Blood and Marrow Transplant Research), National Marrow Donor Program/Be The Match, Minneapolis,

  • The Medical College of Wisconsin, Milwaukee, WI

  • Department of Medicine, Blood and Marrow Transplant Program, Roswell Park Comprehensive Cancer Center, Buffalo, NY

  • Newcastle University, Newcastle Upon Tyne, UK

  • Department of Pediatrics, School of Medicine at Hofstra, New Hyde Park, NY

  • College of Medicine, The Ohio State University, Columbus, OH

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Dermatology

  • Blood/haematological Diseases

Disease

  • Acute lymphoblastic leukemia

  • Alpha-thalassemia myelodysplasia syndrome

  • Squamous cell carcinoma

  • Acute myelocytic leukemia

  • Non-Hodgkin's Lymphoma

  • Non‐Hodgkin Lymphoma

  • keratosis

  • Hodgkin's Lymphoma

  • Breast cancer

  • Neuroblastoma

  • Skin carcinoma

  • Solid malignancies

  • Lymphomas

  • Melanoma

Biomarkers

  • Interferon regulatory factor 4

  • Breakpoint Cluster Region

  • Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Epsilon

  • Interferon

Drug/Treatment

  • Interferon

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A