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: Tolerable Dose of 6-Mercaptopurine and Prognostic Impact of NUDT15-Deficient Genotype in Childhood Acute Lymphoblastic Leukemia

Researchers

Presenter

  • Yoichi Tanaka

Principal Investigators

  • Takaya Moriyama

  • Yuki Arakawa

  • Daisuke Hasegawa

  • Junya Fujimura

  • Dai Keino

  • Atsushi Sato

  • Takahiro Ueda

  • Yuichi Taneyama

  • Masatoshi Takagi

  • Masaki Yamamoto

  • Masaki Matsuoka

  • Moeko Hino

  • Hiroki Hori

  • Katsuyoshi Koh

  • Allen Eng Juh Yeoh

  • Jun J. Yang

  • Atsushi Manabe

Medical Centers

  • Department of Clinical Pharmacy, School of Pharmacy, Kitasato University, Saitama, Japan

  • Department of Pediatric Hematology and Oncology Research, National Research Institute for Child Health and Development, Tokyo, Japan

  • Department of Pharmaceutical Sciences, St Jude Children's Research Hospital, Memphis, TN

  • Department of Hematology/Oncology, Saitama Childrens Medical Center, Saitama, Japan

  • Department of Pediatrics, St. Lukes International Hospital, Tokyo, Japan

  • Department of Pharmacy, St.Marianna University School of Medicine, Kawasaki, Japan

  • Miyagi Children's Hospital, Sendai, Japan

  • Nippon Medical School, Tokyo, Japan

  • Department of hematology/oncology, Chiba children's hospital, Chiba City, JPN

  • Department of Pediatrics and Developmental Biology, Tokyo Medical & Dental Univ., Tokyo, Japan.

  • Sapporo Medical University, Sapporo, Japan

  • Department of Biostatistics, The University of Tokyo, Tokyo, Japan

  • Chiba University, Chiba, JPN

  • Department of Pathologic Oncology, Mie University Graduate School of Medicine, Mie, Japan

  • National University Children's Medical Institute, National University Health System, Singapore, Singapore

  • Department of Pharmaceutical Sciences, St Jude Children's Research Hospital, Memphis, TN

Locations

  • Japan

  • United States

  • Singapore

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

Biomarkers

  • Breakpoint Cluster Region

Drug/Treatment

  • 6-mercaptopurine

  • Methotrexate

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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