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: A Single Mouse Trial Platform for Evaluation of Novel Agents in Acute Lymphoblastic Leukemia By the Pediatric Preclinical Testing Consortium

Researchers

Presenter

  • Richard B. Lock

Principal Investigators

  • Kathryn Evans

  • Tara Pritchard

  • Cara Toscan

  • Chelsea Mayoh

  • Beverly Teicher

  • Raushan T Kurmasheva

  • Peter J Houghton

  • Malcolm Smith

Medical Centers

  • Children's Cancer Institute, Lowy Cancer Research Centre, UNSW, Sydney, Australia

  • National Cancer Institute, Bethesda, MD

  • Greehey Children Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX

Locations

  • Australia

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

Biomarkers

  • Breakpoint Cluster Region

  • Cluster of differentiation 45

  • Second mitochondria-derived activator of caspase

Drug/Treatment

  • birinapant

  • Topotecan Hydrochloride

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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