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: Age but Not Adiposity Predicts Asparaginase-Induced Hepatotoxicity during Induction Therapy for Adolescent and Young Adults with Acute Lymphoblastic Leukemia

Researchers

Presenter

  • Etan Orgel

Principal Investigators

  • Celia Framson

  • Rubi Vazquez

  • David R. Freyer

  • Steven D. Mittelman

Medical Centers

  • Hematology, Oncology, Blood and Marrow Transplantation,Children's Hospital Los Angeles,Los Angeles,United States

  • University of Southern California, Los Angeles, CA

  • Children's Hosp Los Angeles, Los Angeles, CA

  • Division of Endocrinology, UCLA, Los Angeles, CA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Endocrine/metabolic Diseases (ME)

Disease

  • Acute lymphoblastic leukemia

  • Obesity

  • B-cell acute lymphoblastic leukemia

Biomarkers

  • Body mass index

Drug/Treatment

  • Pegaspargase

  • Glucocorticoid

  • Levocarnitine

  • Daunorubicin

  • Asparaginase

  • Vincristine

Outcome

  • N/A

Study Design

  • Prospective

Phase

  • NA

Study Id's

  • NCT02708108

Sponsors

  • N/A

Result

  • N/A

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