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: Comparing the Liver Function of Children with Acute Lymphoblastic Leukemia (ALL) Receiving Standard or High Intensity Treatment during the Interim Maintenance I Phase of Therapy: A Study of 658 Patients

Researchers

Presenter

  • Joanna S. Yi

Principal Investigators

  • Tiffany Simone Chambers

  • Kelly D Getz

  • Michael Scheurer

  • Philip J Lupo

  • Evanette Burrows

  • Marla Daves

  • Richard Aplenc

  • Karen R. Rabin

  • M. Monica Gramatges

Medical Centers

  • Pediatrics, Hematology/Oncology, Baylor College of Medicine, Houston, TX

  • Division of Hematology-Oncology, Texas Children's Hospital, Department of Pediatrics, Baylor College of Medicine, Houston, TX

  • Department of Pathology, The Children's Hospital of Philadelphia, Philadelphia, PA

  • Department of Biomedical and Health Informatics, The Childrens Hospital of Philadelphia, Philadelphia, PA

  • Center for Childhood Cancer Research, Childrens Hospital of Philadelphia, Philadelphia, PA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Endocrine/metabolic Diseases (ME)

Disease

  • Acute lymphoblastic leukemia

  • Obesity

Biomarkers

  • Alanine transaminase

  • Aspartate aminotransferase

  • Breakpoint Cluster Region

  • Creatinine

  • DNA Damage Inducible Transcript 3

  • S-aspartate aminotransferase

Drug/Treatment

  • Methotrexate

Outcome

  • N/A

Study Design

  • Dose Escalation

  • Cohort

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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