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: Epigenetic Drug Combination Overcomes Bone Marrow Microenvironment-Induced Chemoprotection in Pediatric Acute Lymphoblastic Leukemia Via Modulation of CD81

Researchers

Presenter

  • Anthony Quagliano

Principal Investigators

  • Anilkumar Gopalakrisnapillai

  • E. Anders Kolb

  • Sonali Barwe

Medical Centers

  • University of Delaware, Newark, DE

  • Nemours/A. I. duPont Hospital for Children, Wilmington, DE

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • B-cell acute lymphoblastic leukemia

Biomarkers

  • Integrin alpha-4

  • Cluster of Differentiation 29

  • Vascular cell adhesion molecule 1

Drug/Treatment

  • Panobinostat

  • Vidaza

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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