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: STAT3 Is Activated By DYRK1A and Is a Potential Therapeutic Target in B-ALL

Researchers

Presenter

  • Malini Rammohan

Principal Investigators

  • Rahul S. Bhansali

  • Yi-Chien Tsai

  • Alexander Dong

  • Sebastien Malinge

  • Jean-Pierre Bourquin

  • John D. Crispino

Medical Centers

  • Division of Hematology/Oncology, Northwestern University, Chicago, IL

  • College of Medicine, University of Illinois at Chicago, Chicago, IL

  • Department of Paediatric Endocrinology, University Childrens Hospital Zurich, Zurich, Switzerland

  • Telethon Kids Cancer Centre, Subiaco, Australia

Locations

  • United States

  • Switzerland

  • Australia

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Genetic Disorder

Disease

  • Acute lymphoblastic leukemia

  • Down syndrome

  • Solid malignancies

  • B-cell acute lymphoblastic leukemia

Biomarkers

  • L-serine

  • Signal transducer and activator of transcription 3

Drug/Treatment

  • L-Tyrosine

  • C188-9

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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