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: Leukemia Cells Remodel Adipocyte Niches and Their Progenitor Functions to Generate Leukemia Favoring Niche

Researchers

Presenter

  • Bijender Kumar

Principal Investigators

  • Marvin Orellana

  • Jamison Brooks

  • Srideshikan Sargur Madabushi

  • Liliana E Parra

  • Darren Zuro

  • Qiong Wang

  • Ching-Cheng Chen

  • Susanta Hui

Medical Centers

  • Department of Radiation Oncology, City of Hope Medical Center, Duarte, CA

  • Gehr Family Center for Leukemia Research, City of Hope National Medical Center, Duarte, CA

  • Department of pathology, City of Hope National Medical Center, Duarte, CA.

  • Department of Molecular and Cellular Endocrinology, City of Hope Medical Center, Duarte, CA

  • Department of Hematologic Malignancies and Translational Science, City of Hope Medical Center, Duarte, CA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Central Nervous System (CNS)

  • Oncology (ONC)

  • Genetic Disorder

Disease

  • Acute lymphoblastic leukemia

  • Acute myelocytic leukemia

  • Solid malignancies

  • Spinocerebellar ataxia 1

Biomarkers

  • Bone gamma-carboxyglutamic acid-containing protein

  • Breakpoint Cluster Region

  • Cluster of Differentiation 24

  • Cluster of Differentiation 29

  • Interleukin 1 beta

  • Interleukin 6

  • Mesenchymal stem cells

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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