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: TNF-α Driven Inflammation and Mitochondrial Dysfunction Characterize the Platelet Hyperreactivity of Aging and Myeloproliferative Neoplasms (MPN)

Researchers

Presenter

  • Pavel Davizon-Castillo

Principal Investigators

  • Brandon McMahon

  • Sonia Aguila

  • Kenneth L. Jones

  • George D Trahan

  • Katrina J. Ashworth

  • David Bark

  • Robert A. Campbell

  • Kelly Higa

  • Lauren Christine Shih

  • Natalie Saunders

  • James DeGregori

  • Matthew T. Rondina

  • Jorge Di Paola

Medical Centers

  • Children's Hospital Colorado, University of Colorado - Pediatric Hematology/Oncology/BMT, Aurora, CO

  • University of Colorado Denver School of Medicine, Aurora, CO

  • Irish Centre for Vascular Biology, Royal College of Surgeons in Ireland, Dublin, Ireland

  • Center for Cancer and Blood Disorders, Childrens Hospital Colorado, Aurora, CO

  • Pediatric Hematology, Aurora, CO

  • Department of Pediatrics, Section of Hematology/Oncology/BMT, Aurora, CO

  • Colorado State University, Fort Collins, CO

  • Department of Pediatrics and Internal Medicine, University of Utah, Salt Lake City, UT

  • Department of Pediatrics, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO

  • The Program in Molecular Medicine, University of Utah, Salt Lake City, UT

  • Biochemistry and Molecular Genetics, Aurora, CO

  • George E Wahlen VAMC Geriatric Research and Education Clinical Center, Salt Lake City, UT

  • University of Colorado School of Medicine, Lakewood, CO

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Infectious Diseases (ID)

  • Oncology (ONC)

  • Cardiovascular (CVS)

  • Blood/haematological Diseases

  • Pulmonary/Respiratory Diseases

Disease

  • Myeloid neoplasms

  • Tuberculosis

  • Venous thrombosis

Biomarkers

  • Interleukin 1 beta

  • Interleukin 6

Drug/Treatment

  • Phosphatidylserine

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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