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710 : Microrna-142 Deficiency Promotes Chronic Myeloid Leukemia (CML) Transformation from Chronic Phase (CP) to Blast Crisis (BC)

Researchers

Presenter

  • Bin Amber Zhang

Principal Investigators

  • Dandan Zhao

  • Huafeng Wang

  • Chen Liang

  • Le Xuan Truong Nguyen

  • Junjing Qiao

  • Shanshan Suo

  • Yasmin Elhajmoussa

  • Lucy Ghoda

  • David Frankhouser

  • Russell Rockne

  • Ling Li

  • Ya-Huei Kuo

  • Mark Boldin

  • Guido Marcucci

Medical Centers

  • Department of Hematological Malignancies Translational Science, Gehr Family Center for Leukemia Research, Hematology Malignancies and Stem Cell Transplantation Institute, Beckman Research Institute, City of Hope, Duarte, CA

  • Department of Hematological Malignancies Translational Science, Gehr Family Center for Leukemia Research, Hematology Malignancies and Stem Cell Transplantation Institute, Beckman Research Institute, City of Hope, Duarte, CA

  • Department of Hematological Malignancies Translational Science, Gehr Family Center for Leukemia Research, Hematology Malignancies and Stem Cell Transplantation Institute, Beckman Research Institute, City of Hope, Duarte, CA

  • Department of Hematological Malignancies Translational Science, Gehr Family Center for Leukemia Research, Duarte, CA

  • Department of Hematologic Malignancies Translational Science, Gehr Family Center for Leukemia Research, Beckman Research Institute, City of Hope, Duarte, CA

  • City of Hope, Beckman Research Institute, Duarte, CA

  • Beckman Research Institute, Division of Mathematical Oncology, City of Hope National Medical Center, Duarte, CA

  • Department of Hematological Malignancies Translational Science, Gehr Family Center for Leukemia Research, Hematology Malignancies and Stem Cell Transplantation Institute, Beckman Research Institute, City of Hope, Duarte, CA

  • Department of Molecular&Cellular Biology, Beckman Research Institute, City of Hope Medical Center, Duarte, CA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Myeloid neoplasms

  • Acute lymphoblastic leukemia

  • Chronic Myelogenous Leukemia

  • Acute myelocytic leukemia

  • Lymphomas

Biomarkers

  • Breakpoint Cluster Region

  • Cluster of Differentiation 34

  • Cluster of Differentiation 38

Drug/Treatment

  • Tetracycline

  • Nilotinib

  • L-Tyrosine

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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