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3356 : Pre-Transplant Clonal Mosaicism Is Associated with Increased Relapse and Lower Survival in Acute Lymphoblastic Leukemia Patients Undergoing Allogeneic Hematopoietic Cell Transplant

Researchers

Presenter

  • Yiwen Wang

Principal Investigators

  • Junke Wang

  • Ezgi Karaesmen

  • Hancong Tang

  • Philip L. McCarthy

  • Marcelo C. Pasquini

  • Youjin Wang

  • Lisa J. McReynolds

  • Hormuzd Katki

  • Mitchell Machiela

  • Meredith Yeager

  • Loreall Pooler

  • Xin Sheng

  • Christopher Haiman

  • David Van Den Berg

  • Stephen R. Spellman

  • Tao Wang

  • Michelle Kuxhausen

  • Stephen J. Chanock

  • Stephanie J. Lee

  • Alyssa I. Clay-Gilmour

  • Theresa E. Hahn

  • Shahinaz M Gadalla

  • Lara E. Sucheston-Campbell

Medical Centers

  • College of Medicine, The Ohio State University, Columbus, OH

  • Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD

  • Clinical Research Directorate,Frederick National Laboratory for Cancer Research,Bethesda,United States

  • Roswell Park Cancer Institute, Buffalo, NY

  • Center for International Blood and Marrow Transplant Research, Medical College of Wisconsin, Milwaukee, WI

  • Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD

  • National Institute of Health, Bethesda, MD

  • NCI, Rockville, MD

  • National Cancer Institute, Rockville, MD

  • National Cancer Institute, Bethesda, MD

  • Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA

  • University of Southern California Keck School of Medicine, Los Angeles, CA

  • Center for Genetic Epidemiology, Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA

  • Department of Pediatrics, University of Southern California Keck School of Medicine, Los Angeles, CA

  • Center for International Blood and Marrow Transplant Research, Medical College of Wisconsin, Milwaukee, WI

  • The Medical College of Wisconsin, Milwaukee, WI

  • Center for International Blood and Marrow Transplant Research, Minneapolis, MN.

  • Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Bethesda, MD

  • Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA

  • Arnold School of Public Health- Department of Epidemiology & Biostatistics, University of South Carolina, Greenville, SC

  • Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY

  • College of Veterinary Medicine, Cancer Prevention & Control, Columbus, OH

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

Biomarkers

  • Breakpoint Cluster Region

  • Cyclin Dependent Kinase Inhibitor 2A

  • Interleukin 1 alpha

  • Tumor protein p53

Drug/Treatment

  • TP53

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A