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557 : Loss of TET2 Uncouples Proliferative and Effector Functions in CAR T Cells

Researchers

Presenter

  • Nayan Jain

Principal Investigators

  • Zeguo Zhao

  • Archana S. Iyer

  • Michael Lopez

  • Judith Feucht

  • Richard P. Koche

  • Yingqian Zhan

  • Michel Sadelain

Medical Centers

  • Louis V. Gerstner Sloan Kettering Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY

  • Center for Cell Engineering and Immunology Program, Memorial Sloan Kettering Cancer Center, New York City, NY

  • Memorial Sloan Kettering Cancer Center, Port Washington, NY

  • Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY

Locations

  • United States

  • Germany

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Chronic Lymphocytic Leukemia

  • Cytokine release syndrome

  • Lymphomas

  • Solid malignancies

  • B-cell acute lymphoblastic leukemia

Biomarkers

  • Coxsackie Virus And Adenovirus Receptor

Drug/Treatment

  • Midotens

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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