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493 : Influence of Inherited and Acquired Hematological and Immunological Gene Variants on the Outcomes of Allogeneic Hematopoietic Stem Cell Transplantation in Patients with Hematological Malignancies

Researchers

Presenter

  • Zhihui Li

Principal Investigators

  • Yongqiang Zhao

  • Yanzhi Song

  • Caiyan Zhang

  • Qinlong Zheng

  • Chunrong Tong

  • Tong Wu

Medical Centers

  • Bone Marrow Transplantation, Beijing Boren Hospital, Beijing, China

  • Department of Hematology Pathology, beijing, China

  • Laboratory of Molecular Diagnostics, Beijing Borenhospital, Beijing, China

  • Hematological Pathology, Beijing Boren Hospital, Beijing, China

Locations

  • China

Companies

  • N/A

Study Components

Therapeutic Area

  • Genetic Disorder

Disease

  • Hemophagocytic lymphohistiocytosis

  • Acute lymphoblastic leukemia

  • Hematological malignancies

  • Graft-versus-host disease

  • Acute myelocytic leukemia

  • Non-Hodgkin's Lymphoma

  • Hodgkin's Lymphoma

  • Fanconi anemia

  • Non‐Hodgkin Lymphoma

  • Lymphomas

  • Anemia

  • Fanconi anemia, complementation group A

  • Lipopolysaccharide (LPS)‐responsive and beige‐like anchor protein deficiency

Biomarkers

  • Mismatch repair endonuclease PMS2

  • MutS Homolog 6

  • Neurogenic locus notch homolog protein 1

  • Nucleophosmin 1

  • Breast cancer type 1 susceptibility protein

  • Breast cancer type 2 susceptibility protein

  • Nucleotide-binding oligomerization domain-containing protein 2

  • Complement Factor B

  • CREB-binding protein

  • DNA methyltransferase 3 alpha

  • Fanconi anaemia, complementation group A

  • Fms related tyrosine kinase 3

  • GTPase Nras

  • Isocitrate dehydrogenase 2

  • KIT Proto-Oncogene, Receptor Tyrosine Kinase

  • KRAS proto-oncogene, GTPase

  • Liver kinase B1

  • Tumor protein p53

  • Unc-13 Homolog D

  • BRCA1 interacting protein

  • Ataxia-telangiectasia mutated

Drug/Treatment

  • Mycophenolate mofetil

  • CKD-4101

  • Cyclosporine eent

  • Methotrexate

  • fludarabine tablet

  • Busulfan

  • Allopurinol

  • TP53

Outcome

  • N/A

Study Design

  • Cohort

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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