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2343 : Enhancing the Antigen-Sensitivity of the CD22 CAR through Modulation of the Affinity and Linker-Length of the Single-Chain Fragment Variable

Researchers

Presenter

  • Mark Eric Kohler

Principal Investigators

  • Zachary Walsh

  • Kole Degolier

  • Terry J. Fry

Medical Centers

  • Center for Cancer and Blood Disorders, Childrens Hospital Colorado and the University of Colorado School of Medicine, Aurora, CO

  • University of Colorado Anschutz, Aurora, CO

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

Biomarkers

  • Breakpoint Cluster Region

  • Cluster of Differentiation 25

  • Cluster of differentiation 69

  • Extracellular signal-regulated kinase

  • Interleukin-2

  • T cell activity

Drug/Treatment

  • Interferon Gamma

  • Interleukin

  • Interferon

Outcome

  • N/A

Study Design

  • N/A

Phase

  • I

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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