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1891 : A Novel Engineered Single-Chain Antibody Fragment for Targeting Pediatric Philadelphia Chromosome-like Acute Lymphoblastic Leukemia

Researchers

Presenter

  • Sara M.A. Mohamed

Principal Investigators

  • Keith Sia

  • Karl-Heinz Friedrich

  • Andreas Wohlmann

  • Savvas Savvides

  • Peter Schofield

  • Daniel Christ

  • Maria Kavallaris

  • Richard B. Lock

  • Narges Bayat

Medical Centers

  • Department of Clinical Pharmacy, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt

  • Children's Cancer Institute, School of Women’s and Children’s Health, UNSW Sydney, Sydney, NSW, Australia

  • Institute of Biochemistry II, Jena University Hospital, Jena, Germany

  • VIB-UGent Centre for Inflammation Research, Gent, Belgium

  • Garvan Institute of Medial Research, Sydney, New South Wales, Australia.

  • St. Vincent’s Clinical School, Faculty of Medicine, UNSW Sydney, Sydeny, Australia

  • Australian Centre for Nanomedicine, ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, UNSW Sydney, Sydney, Australia

  • Children's Cancer Inst. Australia Lowy Cancer Research Centre, Univ N.S.W., Randwick, NSW, Australia

Locations

  • Egypt

  • Australia

  • Germany

  • Belgium

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

Biomarkers

  • Breakpoint Cluster Region

  • Peripheral blood mononuclear cell

  • Phosphorylated signal transducer and activator of transcription 5

  • Signal transducer and activator of transcription 5

Drug/Treatment

  • N/A

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A